Publications 2010

Animal studies

Hou L, Vaag A, Nielsen MO: Nutrition restriction in late-gestation and postnatal overfeeding change metabolic preferences in skeletal muscle longussimus dorsi of sheep. EAAP Publication No. 127, 2010: 187-188.

Josefsen K, Lee YC, Thams P, Efendic S, Nielsen JH. AKAP 18 α and γ have opposing effects on insulin release in INS 1E cells. FEBS Letters 584:81-85, 2010.

Nyberg NT, Nielsen MO, Jaroszewski JW: Metabolic trajectories based on 1H NMR spectra of urines from sheep exposed to nutritional challenges during prenatal and early postnatal life. Metabolomics 2010;6(4): 489–496.

Human physiological and clinical studies

Produced under network grant “Global maternal and fetal care in prevention of adult non-communicable disease” from the Danish Council for Strategic Research (no. 09-063072)

Alibegovic AC, Højbjerre L, Sonne MP, van Hall G, Alsted TJ, Kiens B, Stallknecht B, Dela F, Vaag A. Increased rate of whole body lipolysis before and after 9 days of bed rest in healthy young men born with low birth weight. Am J Physiol Endocrinol Metab. 2010;298(3):E555-64.

Andersson EA, Pilgaard K, Pisinger C, Harder MN, Grarup N, Færch K, Sandholt C, Poulsen P, Witte DR, Jørgensen T, Vaag A, Pedersen O, Hansen T. Do gene variants influencing adult adiposity affect birth weight? A population-based study of 24 loci in 4,744 Danish individuals. PLoS One. 2010;5(12):e14190.

Andersson EA, Pilgaard K, Pisinger C, Harder MN, Grarup N, Faerch K, Poulsen P, Witte DR, Jørgensen T, Vaag A, Hansen T, Pedersen O. Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birth weight. Diabetologia. 2010;53(9):1908-16.

Brøns C, Jacobsen S, Nilsson E, Rönn T, Jensen CB, Storgaard H, Poulsen P, Groop L, Ling C, Astrup A, Vaag A. Deoxyribonucleic acid methylation and gene expression of PPARGC1A in human muscle is influenced by high-fat overfeeding in a birth weight-dependent manner. J Clin Endocrinol Metab. 2010;95(6):3048-56.

Friedrichsen M, Poulsen P, Richter EA, Hansen BF, Birk JB, Ribel-Madsen R, Stender-Petersen K, Nilsson E, Beck-Nielsen H, Vaag A, Wojtaszewski JF. Differential aetiology and impact of phosphoinositide 3-kinase (PI3K) and Akt signalling in skeletal muscle on in vivo insulin action. Diabetologia. 2010;53(9):1998-2007.

Pilgaard K, Færch K, Carstensen B, Poulsen P, Pisinger C, Pedersen O, Witte DR, Hansen T, Jørgensen T, Vaag A. Low birth weight and premature birth are both associated with type 2 diabetes in a random sample of middle-aged Danes. Diabetologia. 2010;53(12):2526-30.

Ribel-Madsen R, Brøns C, Friedrichsen M, Poulsen P, Vaag A. Retinol-binding protein 4 in young men with low versus normal birth weight: physiological response to short-term overfeeding. Obesity (Silver Spring). 2011;19(6):1304-6.

Sonne MP, Alibegovic AC, Højbjerre L, Vaag A, Stallknecht B, Dela F. Effect of 10 days of bedrest on metabolic and vascular insulin action: a study in individuals at risk for type 2 diabetes. J Appl Physiol. 2010;108(4):830-7.

Sonne MP, Højbjerre L, Alibegovic AC, Vaag A, Stallknecht B, Dela F. Diminished insulin-mediated forearm blood flow and muscle glucose uptake in young men with low birth weight. J Vasc Res. 2010;47(2):139-47.

Population-based studies

Halldorsson TI, Petersen SB, Strøm M, Olsen SF. Intake of artificially sweetened soft drinks and risk of preterm delivery: a prospective cohort study of 59,334 Danish pregnant women. Am J Clin Nutr 2010;92(3):626-33.

Sun Y, Vestergaard M, Christensen J, Olsen J, Olsen SF. Intake of marine n-3 fatty acids during pregnancy and risk for epilepsy in the offspring: a population-based cohort study. Epilepsy Research 2010;91(2-3):267-72.